Sujet de la discussion : MedeSpace.Net :: Lycéens au bloc opératoire! :D

Publié par La Pharmacienne le 05-12-2009 16:06
#31

J'ai oublié de citer au début la définition du Propofol! la voici:


Propofol

Propofol (INN, marketed as Diprivan by AstraZeneca) is a short-acting, intravenously administered hypnotic agent. Its uses include the induction and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation. Propofol is also commonly used in veterinary medicine. Propofol is approved for use in more than 50 countries, and generic versions are available.

Chemically, propofol is unrelated to barbiturates, and has largely replaced sodium thiopental (Pentothal) for induction of anesthesia as recovery from propofol is more rapid and "clear" as compared to thiopental. Propofol is not considered an analgesic, so opioids such as fentanyl may be combined with propofol to alleviate pain.[1] Due to its amnestic effects and appearance as a white liquid, propofol has been humorously dubbed "milk of amnesia" by medical professionals.[2]



Références:
[1] Miner JR, Burton JH. Clinical practice advisory: Emergency department procedural sedation with propofol. Annals of Emergency Medicine. 2007 Aug;50(2):182–7, 187.e1. Epub 2007 Feb 23.

[2] Euliano TY, Gravenstein JS (2004). "A brief pharmacology related to anesthesia". Essential anesthesia: from science to practice. Cambridge, UK: Cambridge University Press. pp. 173. ISBN 0-521-53600-6. http://books.goog...C&pg=PA173. Retrieved 2009-06-02.